Professor Michael Fenech is recognised internationally for his research in nutritional genomics and genetic toxicology. His pioneering research led to the development of the International Standard DNA damage test (CBMN assay), endorsed by the International Atomic Energy Agency and the OECD. This research expands to the identification of six biomarkers of DNA damage and cytotoxicity; and its published in Nature Protocols.
His key goal is to determine the nutritional and environmental requirements for DNA damage prevention. In 2003 Dr Fenech proposed a novel ageing and disease prevention strategy based on personalised diagnosis and prevention of DNA damage by appropriate diet/life-style intervention, which has led to the Genome Health Clinic concept.
In 2003-2009 his laboratory further developed the CBMN assay into a ‘cytome’ assay consisting of six complementary biomarkers of DNA damage and cytotoxicity which is now published in Nature Protocols.
Professor Fenech’s research explores (i) the impact of nutrition and psychological stress on chromosomal and telomere integrity and (ii) personalised nutrition for diabetes and dementia prevention and for cancer growth control. He co-founded the HUMN project on micronuclei in human populations in 1997 and the Asia Pacific Nutrigenomics Nutrigenetics Organisation in 2014. Since 2010 he has been an invited speaker at 59 international conferences 10 plenary lectures
Join Professor Michael Fenech in learning about the epigenetic effects of ageing and environmental factors. Explore emerging evidence about the role of dietary factors in promoting epigenetic changes in aging.
Discover which epigenetic profiles are/are not robust predictors of health outcomes and the causes of epigenetic changes predicting beneficial/adverse health outcomes. Discuss the epigenetic effects of micronutrients and develop new knowledge on how to make dietary recommendations to prevent accelerated aging caused by genetic modification. Consider the influence of nutrition and environmental factors in reversing age-related epigenetic ‘drift’ and discuss safe and effective measurable therapeutic interventions
“Epigenetic Changes with Age”, provides an overview of everything you need to know about the epigenome, discusses the importance of epigenetic drift as one of the fundamental hallmarks of ageing, and explores the prospects of rejuvenation by reversing deleterious epigenetic marks” Prof. Michael Fenech