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High-Demand Amino Acids Could Play an Important Role in Supporting Recovery in Medical Practice

Access

12 months

Format

Online Webinar

Duration

1 hour

Presenter

Hugh Dunstan

The High-Demand Amino Acids (HDAA) are a newly identified group of amino acids that have pivotal roles in metabolism, comprising histidine, serine, glycine, lysine, ornithine, and aspartic acid.

These HDAA are critical to the functioning of numerous biochemical pathways, as well as fuelling protein synthesis. Glycine, a standout contributor, holds a pivotal one-third composition of collagen proteins, underscoring its structural significance. Despite their critical role, HDAA face rapid depletion through sweat, urine, and the rigors of daily life—intensified during daily activities, trauma, infections, and exercise.

Remarkably, the body does not hold stores of amino acids, resorting to the catabolism of muscle proteins to meet HDAA demands. In the dynamic landscape of medical practice, the introduction of HDAA through exogenous supplementation emerges as a highly effective strategy. Swift absorption without the need for digestion provides reduced demand for muscle catabolism.

This breakthrough not only preserves muscle mass but holds the key to enhancing recovery from illness and strenuous exercise. The proposal to replenish HDAA at levels equivalent to daily deficits emerges as a promising strategy, offering a targeted approach to supplementation in the pursuit of enhanced health and recovery.

In this webinar you will learn: 

  • The composition and crucial metabolic roles of High-Demand Amino Acids (HDAA)
  • The importance of HDAA in fueling protein synthesis and their essential contribution to various biochemical pathways.
  • The rapid depletion of HDAA through daily activities, trauma, infections, and exercise, and the body’s reliance on muscle protein catabolism to meet HDAA demands.
  • The potential of exogenous HDAA supplementation as an effective strategy in medical practice, ensuring swift absorption without the need for digestion.
  • The absence of amino acid stores in the body and the resulting catabolism of muscle proteins to fulfill HDAA requirements.
  • The proposal to replenish HDAA levels to match daily deficits, offering a targeted approach to supplementation for improved health and recovery.

Join Hugh Dunstan, PhD, in the webinar 'High-Demand Amino Acids Could Play an Important Role in Supporting Recovery in Medical Practice'.

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MEET YOUR PRESENTER

Hugh Dunstan

PhD, CEO
Hugh Dunstan has been a university researcher for 40 years and he recently retired in 2020 as a Professor from the University of Newcastle, Australia. He is a highly accomplished research scientist with a vast knowledge of biochemistry, where his research focus was the nature of exercise-induced fatigue and the metabolic processes that underpin it. Hugh worked closely for many years with Professor Tim Roberts and Dr Margaret MacDonald and in 2014, they made a significant breakthrough in understanding the significance of the losses of amino acids in sweat and urine, relative to their corresponding blood levels. This breakthrough provided new insights into the supply and demand for key nutrients in humans and has opened up a completely new understanding of protein turnover and amino acid metabolism.

Over the next six years, Hugh and his team continued to investigate amino acid losses in sweat and urine from humans and have published their findings in international peer-reviewed journals. Their research has identified six amino acids that are lost in large quantities in sweat and urine. These same six amino acids have numerous metabolic roles in the body in major areas of body functions: Energy Systems, Growth and Recovery, Structural Integrity and Metabolism. Because of these features, this group of amino acids has been referred to as high-demand amino acids (HDAA). This scientific revelation has led to the formation of InnovAAte Pty Ltd and the development by of novel HDAA supplementation products: ElectrAAte® and OptimatAAte®. The goals of these products are simply to replenish the HDAA and electrolytes for maintaining optimal hydration and an enhanced healthy lifestyle.

A key mission of InnovAAte is to promote the research findings to health professionals and the general public. This insight will give them some tools to better balance key nutrient demands generated by active and healthy lifestyles. Hugh’s research has had a significant impact on the scientific community and has provided a new perspective on the importance of HDAA in maintaining proper hydration and assisting muscle recovery.