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The Importance of Histidine Supplementation in Health and Wellbeing

Access

12 months

Format

Online Webinar

Duration

1 hour

Presenter

Emeritus Professor Roberts

In this webinar series Emeritus Professor Roberts will introduce the newly identified High Demand Amino Acids (Aspartic Acid, Glycine, Histidine, Lysine, Ornithine, Serine) that have pivotal roles in metabolism, in the functioning of numerous biochemical pathways, as well as fuelling protein synthesis.

Despite their critical roles, HDAA face rapid depletion through sweat, urine, and the rigors of daily life—intensified during daily activities, trauma, infections, and exercise. HDAA supplementation can accelerate the natural body recovery processes to maintain good health, retain muscle mass, reduce fatigue, feel more energetic, improve stamina, general well-being, sleep and recovery from illness, injury or intensive physical activity. This webinar will then focus on histidine and its critical roles in energy production, immunity and inflammation.

Histidine is an amino acid that regulates body functions including wakefulness, feeding behaviour, digestion and motivation. It is required for synthesis of haemoglobin and a deficit can lead to anaemia. Histidine is required for the formation of carnosine which is highly concentrated in the muscles and brain and has many roles including acting as an antioxidant.

Histidine is crucial for the maintenance and proper functioning of the immune system. Histidine supplementation can influence the signalling proteins that mediate inflammation and immune responses. Histidine is an essential precursor for the important neurotransmitter histamine.
Histamine has vital roles in 23 different physiological functions (sleep, gut function, brain function, allergy & arousal), modulated through four different histamine receptors.

Supplemental histidine is being investigated for use in a variety of different conditions, including neurological disorders, atopic dermatitis, metabolic syndrome, diabetes, uraemic anaemia, ulcers, inflammatory bowel diseases, malignancies, and muscle performance during strenuous exercise.

Join Emeritus Professor Tim Roberts in the webinar ‘The Importance of Histidine Supplementation in Health and Wellbeing.’
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MEET YOUR PRESENTER

Emeritus Professor Tim Roberts

AM, FRSN, PhD
Emeritus Professor Tim Roberts is a scientist interested in Chronic Fatigue Syndrome, chronic infection, sports supplements, amino acid supplements, who currently focuses on metabolomics of chronic disease. In association with long-time collaborator Professor Hugh Dunstan their multidisciplinary research group has been investigating underlying biochemical and microbiological anomalies in polysymptomatic illness and in exercise.   

They developed and published a computer-based model to investigate amino acid intake, utilisation and loss. The model allowed a completely new understanding of protein turnover and amino acid metabolism that included an ability to understand: the quantity of amino acids losses in sweat; the nature of amino acid losses in sweat; the direct relationship to important aspects of human biology, protein turnover and metabolism; and how amino acids contribute to health, well-being, exercise and recovery.Of the 20 amino acids used by the body to build proteins, the researchers found that there are six amino acids that are lost daily in significant quantities. These amino acids play crucial roles in various bodily functions, general health, well-being, and recovery from injury or illness, and are essential for metabolism and protein synthesis. Remarkably, the body does not hold stores of amino acids, resorting to the catabolism of muscle proteins to meet HDAA demands. In the dynamic landscape of medical practice, the introduction of HDAA through exogenous supplementation emerges as a highly effective strategy. Swift absorption without the need for digestion provides reduced demand for muscle catabolism.

This novel insight led to development of two unique nutritional supplement strategies:Well-being: The supply of high-demand amino acids that optimise the body’s ability to support general exertion, build and maintain energy systems and support collagen synthesis. Hydration: The supply of high-demand amino acids plus the key electrolytes needed to maintain/restore hydration, whilst helping the body to generate and utilise energy, and support recovery.

In 2017 the group were able to establish InnovAAte Pty Ltd to commercialise the patented laboratory findings. Tim now spends his week working to develop the company as one of its Directors.